BRILINTA (Ticagrelor) 90mg

Brilinta (Ticagrelor) Detailed Medicine Description

Drug Class:
Platelet Aggregation Inhibitor (P2Y12 receptor antagonist)

Categories:
Antiplatelet, Cardiovascular Medicine

Active Ingredient Name:
Ticagrelor

Popular and Other Names:

• Brilinta (brand name)
• Ticagrelor (generic name)
• Brilique (used in Europe)
• Possia (alternate brand in some regions)

Mode of Action

Brilinta (Ticagrelor) works by inhibiting platelet aggregation, which helps to prevent blood clots from forming. It blocks the P2Y12 receptor on the platelets, stopping ADP (adenosine diphosphate) from binding to the receptor. By doing this, Ticagrelor reduces the ability of the blood to clot, thus lowering the risk of heart attack or stroke in patients with acute coronary syndrome or those undergoing certain heart surgeries.

How to Use Brilinta

Administration:
Brilinta is taken orally in tablet form, with or without food. Swallow the tablet whole with water.

Timing:

• Take Brilinta at the same time every day, ideally as prescribed by your doctor.
• If you miss a dose, take it as soon as you remember unless it's close to the time of your next dose.

Important Usage Notes:

• Never stop taking Brilinta without consulting your healthcare provider, as this could increase the risk of heart attack or stroke.
• Avoid taking other medications that increase bleeding risks, such as aspirin (unless prescribed by your doctor in low doses).

Recommended Dosage

• Standard Dosage for Adults:
  The initial dose is usually 180 mg (two 90 mg tablets) as a loading dose, followed by a maintenance dose of 90 mg twice daily.

• Dosage with Aspirin:
  Brilinta is often prescribed along with low-dose aspirin (usually 75-100 mg daily) for optimal results.

• Special Cases:
  In certain high-risk conditions, your doctor may adjust the dosage based on your clinical profile. Always follow the dosage instructions from your healthcare provider.

Directions

1. Timing:
   Take the medication twice daily, once in the morning and once in the evening.

2. Storage:
   Store the tablets in a cool, dry place, away from direct sunlight. Keep them out of reach of children.

3. Dietary Considerations:
   Brilinta can be taken with or without food.

4. Missed Dose:
   If you miss a dose, take it as soon as possible unless it is almost time for the next dose. Do not double the dose to catch up.

Cautions

• Allergic Reactions:
  If you experience signs of an allergic reaction, such as difficulty breathing, swelling, or hives, seek medical attention immediately.

• Bleeding Risk:
  Brilinta increases the risk of bleeding. Avoid using other blood-thinning medications (like warfarin) unless prescribed.

• Surgery or Dental Procedures:
  Inform your doctor or dentist that you are taking Brilinta before any surgery or procedure to avoid excessive bleeding.

• Interactions:
  Do not take Brilinta with certain antifungal medications, blood thinners, or high doses of aspirin unless advised by your doctor.

• Pregnancy & Breastfeeding:
  Consult your doctor if you are pregnant, planning to become pregnant, or breastfeeding while on Brilinta.

Managing Side Effects

• Common Side Effects:

  • Shortness of breath
  • Easy bruising
  • Nosebleeds
  • Dizziness
  • Headaches

  Management:
  If you experience mild side effects like headaches or dizziness, monitor them and consult your healthcare provider if they worsen. For minor bleeding, apply pressure to the affected area. If side effects persist or intensify, seek medical help.

• Serious Side Effects:

  • Severe bleeding (internal or external)
  • Blood in urine or stool
  • Unexplained, prolonged bleeding
  • Sudden or severe shortness of breath

  Action:
  In the event of serious side effects, stop the medication and seek emergency medical assistance immediately.

Guidelines

• Avoid Alcohol:
  Consuming alcohol while taking Brilinta can increase your risk of stomach bleeding.

• Regular Monitoring:
  Your doctor may recommend periodic blood tests to monitor your response to the medication and check for bleeding risks.

• Aspirin Usage:
  You should not take aspirin in doses above 100 mg per day while on Brilinta unless your doctor advises otherwise.

• Inform Healthcare Providers:
  Always tell your healthcare providers that you are taking Brilinta, especially before undergoing surgeries or dental work.

Frequently Asked Questions (FAQs)

1. What is Brilinta used for?
   Brilinta is used to prevent heart attacks and strokes in individuals with acute coronary syndrome (ACS) or those undergoing stent placement or other heart surgeries.

2. Can I take Brilinta with aspirin?
   Yes, Brilinta is often prescribed with low-dose aspirin (75-100 mg daily) to prevent blood clots.

3. How long should I take Brilinta?
   The duration of Brilinta therapy depends on your health condition and your doctor's advice. In many cases, it is taken for at least 12 months following a heart-related event.

4. What should I do if I miss a dose?
   Take the missed dose as soon as you remember, unless it's almost time for your next dose. Do not double your dose.

5. Can Brilinta cause shortness of breath?
   Yes, shortness of breath is a common side effect of Brilinta. If it becomes severe, consult your healthcare provider immediately.

6. Can I drink alcohol while taking Brilinta?
   It is best to avoid alcohol while taking Brilinta as it can increase the risk of bleeding.